Effects of intestinal microbiota on cognitive development in preterm infants with intraventricular hemorrhage

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300069895

Enrollment

Unknown

Registered

2023-03-29

Start date

2023-04-01

Completion date

Unknown

Last updated

2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

premature

Interventions

Group of premature:None

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Informed consent of the legal guardian; 2. Premature infants, gestational age (GA) < 37 weeks; 3. Intestinal flora within 1 week after birth.

Exclusion criteria

Exclusion criteria: 1. Time to survive for all causes< 3 years; 2. social factors abandon treatment; 3. Children with a predisposition to the disease at the age of 3 years who cannot be clearly excluded or diagnosed with language development disorder or autism spectrum disorder; 4. Brain injury other than intraventricular hemorrhage diagnosed in the neonatal period; 5. Other neurological disorders during follow-up; 6. Inflammatory bowel disease, chronic diarrhoea, immune-related disease, and diabetes were confirmed during follow-up.

Design outcomes

Primary

Measure	Time frame
intraventricular hemorrhage;Language developmental disorders;Autism spectrum disorders;	—

Countries

China

Contacts

Public ContactXinlin Hou

Peking University First Hospital

vivianmayi@126.com+86 13552296675

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026