nasopharyngeal carcinoma
Conditions
Interventions
Gold Standard:Histopathological examination, imaging examination and other confirmation methods commonly used in clinical practice, etc.
Index test:anti-EBV BNLF2b antibody
Sponsors
Zhongshan City People's Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 94 Years
Inclusion criteria
Inclusion criteria: 1. Gender and age are not limited 2. Subjects have symptoms or signs suspected of NPC 3. Subjects diagnosed with head and neck tumors except NPC 4. Subjects diagnosed with EBV associated benign or malignant disease 5. Subjects being positive for EBV antibodies or EBV DNA 6. Subjects require differential diagnosis of NPC during endoscopic and other imaging examinations 7. Subjects whom the investigator deems appropriate for inclusion based on clinical judgment and experience
Exclusion criteria
Exclusion criteria: 1. Subjects whom the investigator deems inappropriate for inclusion, based on clinical judgment, potential risks, or other concerns 2. Subjects without testing results of reference standard to confirm or exclude of NPC 3. Samples collected from subjects meet any of the following conditions, the subjects should be excluded ?Samples collected from subjects that are severely hemolyzed, deteriorated, chylous, or obviously contaminated by microorganisms, or other experimentally unsuitable samples ?Samples that cannot be traced back or those with incomplete sample information. ?Samples collected from subjects that do not meet the requirements for collection, processing, preservation, and transportation 4. Retain only the earliest sample from each subject for analysis, except for samples from different clinical stages or pre- and post-treatment in NPC cases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity;Area under curve; | — |
Secondary
| Measure | Time frame |
|---|---|
| Kappa; | — |
Countries
China
Contacts
Public ContactJi Mingfang
Zhongshan City People's Hospital
Outcome results
None listed