Clinical research protocol of exploring the artificial intelligence-assisted CT quantitative identification model of esophagogastric varices in patients with portal hypertension

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300069865

Enrollment

Unknown

Registered

2023-03-28

Start date

2022-05-06

Completion date

Unknown

Last updated

2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophagogastric varices

Interventions

Case series:None

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Patients who underwent gastroscopy after April 1, 2021 at the Endoscopy Center of Department of Gastroenterology, West China Hospital, Sichuan University. The CT images of patients from April 1 to June 30 were used as the training set, and the CT images of patients after July were used as the validation set of a single center. The CT images of patients who underwent gastroscopy in the endoscopy centers of the hospitals that participated in the competitive enrollment after July 2021 were used as the multicenter validation set. (2) Final diagnosis of esophageal varices by experienced endoscotists (positive group) or no abnormalities in the esophagus (negative group). (3) Patients in the positive group underwent abdominal enhanced CT imaging examination (including upper abdominal enhanced CT, whole abdominal enhanced CT, upper abdominal CTA, whole abdominal CTA, etc.) within 3 months before and after gastroscopy. Patients in the negative group underwent abdominal enhanced CT imaging examinations (including upper abdominal enhanced CT, whole abdominal enhanced CT, upper abdominal CTA, whole abdominal CTA, etc.) from April 1, 2020 to December 31, 2021.

Exclusion criteria

Exclusion criteria: (1) Endoscopic treatment and intervention were performed before imaging data. (2) Repeated endoscopic treatment after imaging data (=2 times). (3) poor quality of imaging data or incomplete clinical data. (4) previous esophageal or gastric surgery or esophageal mucosal lesions. (5) endoscopic ultrasonography and bedside endoscopy. (6) complicated with gastrointestinal bleeding and hepatoma.

Design outcomes

Primary

Measure	Time frame
Sensitivity;Specificity;	—

Secondary

Measure	Time frame
Bleeding rate;Rebleeding rate;Portal vein width;	—

Countries

China

Contacts

Public ContactKai Deng

Department of Gastroenterology and Hepatology, West China Hospital of Sichuan University

dengkai@wchscu.cn18224451156

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026