Cholangiocarcinoma
Conditions
Interventions
Biliary obstruction group:None
Sponsors
Sichuan University, West China Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: The patients included in this study must simultaneously meet the following criteria: 1) Obstructive jaundice as the main initial symptom; 2) Imaging (CT and MRI) is difficult to distinguish from malignant biliary obstruction through expert interpretation; 3) Confirmed pathological diagnosis in our center via at least one methods (postoperative pathology or endoscopic ERCP biopsy); 4) Between the ages of 18 and 80.
Exclusion criteria
Exclusion criteria: Patients were excluded if any of the following criteria were met: 1) Patients with malignant biliary obstruction and distant metastasis confirmed by radiological methods; 2) Patients with biliary obstruction confirmed pathologically as non-biliary origin; 3) Patients younger than 18 years or older than 80 years.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Relative expression levels of exosomal circ-SIAE in bile;Relative expression levels of circ-CAPRIN1 in bile;Gold standard: pathological diagnosis of biliary obstruction (postoperative pathology or percutaneous biopsy or ERCP biopsy); | — |
Secondary
| Measure | Time frame |
|---|---|
| Relative expression levels of exosomal circ-SIAE in serum;Relative expression levels of circ-CAPRIN1 in serum; | — |
Countries
China
Contacts
Public ContactXianze Xiong
Sichuan University, West China Hospital
Outcome results
None listed