painless gastrointestinal endoscopy
Conditions
Interventions
PE1:Esketamine 0.05mg/kg
PE2:Esketamine 0.1mg/kg
PE3:Esketamine 0.2mg/kg
PS:Sufentanil 0.1µg/kg
Sponsors
The Second Affiliated Hospital of Shantou University Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 59 Years
Inclusion criteria
Inclusion criteria: 1)Adult patients ( age from 18 to 59 years ) scheduled for painless gastroscopy, regardless of gender. 2)Subjects clearly understand and voluntarily participate in this study,and then sign informed consent form. 3)ASA grade I-II.
Exclusion criteria
Exclusion criteria: 1)ASA grade III or myocardial infarction within 6 month 2)Irregular medication or uncontrolled high blood pressure 3)Chronic lung disease or recent history of pneumonia. 4)Decompensation of the liver or kidney. 5)Neuropsychiatric disorders; Epilepsy; A long history of psychoactive drug use. 6)Predictable difficult airway. 7)lactating women. 8)Allergies to eggs, seafood, soy or the drug in experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| heart rate;blood pressure;blood oxygen saturation;recovery time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse reactions;Incidence of bucking; | — |
Countries
China
Contacts
Public ContactZhang Yong-fa
The Second Affiliated Hospital of Shantou University Medical College
Outcome results
None listed