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Effect of kuanxiong aerosol on coronary microcirculation in patients with unstable angina pectoris during PCI

Effect of kuanxiong aerosol on coronary microcirculation in patients with unstable angina pectoris during PCI

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300069831
Enrollment
Unknown
Registered
2023-03-27
Start date
2021-02-01
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary heart disease

Interventions

Sponsors

Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Between 18 and 80 years of age; (2) Coronary angiography showed that the stenosis of the proximal and middle segment of the anterior descending artery was >70%, and coronary intervention was planned; (3) Patients requiring FFR during PCI; (4) One month before admission, he did not take aromatic Wentong traditional Chinese medicine preparations; (5) TCM diagnosis is clear, and the syndrome differentiation has qi stagnation / blood stasis / phlegm obstruction / cold coagulation syndrome; (6) Sign the informed consent of the study and the informed consent of the operation.

Exclusion criteria

Exclusion criteria: (1) Pregnant and lactating patients (2) Known and definite allergy to the main components of the wide chest aerosol (3) Severe cardiac insufficiency (left ventricular ejection fraction 3 mg/dl or 265.2umol/l); (5) Malignant tumor or hematological disease; (6) Dementia patients

Design outcomes

Primary

MeasureTime frame
index of microcirculation resistance;

Secondary

MeasureTime frame
Coronary artery blood flow reserve fraction;troponin I;creatine kinase isoenzyme;30days MACE(Major Adverse Cardiovascular Events);

Countries

China

Contacts

Public ContactLiu Hongxu

Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University

bjzyyylzh@163.com87906633

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 6, 2026