Hysteroscopy
Conditions
Interventions
E1:esketamine 0.25mg/kg composite propofol
E2:esketamine 0.3mg/kg composite propofol
E3:esketamine 0.35mg/kg composite propofol
E4:esketamine 0.4mg/kg composite propofol
F:fentanyl 1ug/kg composite propofol
Sponsors
Chengdu Wenjiang District People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Patients undergoing hysteroscopic intravenous anesthesia;2.Age 18-60 years old;3.Operation time = 30min;4.ASA grade I-III;5.18kg/m2<BMI<28kg/m2;6.Sign an informed consent for anesthesia.
Exclusion criteria
Exclusion criteria: 1.Patients who are allergic to esketamine or propofol or fentanyl;2.Patients with poorly controlled hypertension or unstable angina pectoris; 3.Preeclampsia and eclampsia;4.Poorly controlled hyperthyroidism(hyperthyroidism);5.Patients with a history of mental and neurological diseases;6.Patients with a history of opioid and esketamine addiction;7.Hysteroscopic patients who refuse to perform intravenous general anesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of Sedation;Hemodynamic index;Incidence of respiratory depression during operation;Incidence of intraoperative hypotension;Mean time interval of propofol addition; | — |
Secondary
| Measure | Time frame |
|---|---|
| Onset time;Awakening time;Adverse reactions after surgery;Evaluation of patient satisfaction; | — |
Countries
China
Contacts
Public ContactLiu Xu
Chengdu Wenjiang District People's Hospital
Outcome results
None listed