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Effect of Esketamine on the threshold of mechanical pain after cesarean section

Esketamine prevents chronic pain in puerperae after cesarean section

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300069812
Enrollment
Unknown
Registered
2023-03-27
Start date
2023-03-27
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain after cesarean section

Interventions

S group :Esketamine intravenous pump 0.25 mg/kg
C group :Normal saline is pumped intravenously

Sponsors

West China Second Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: The patient voluntarily cooperates and signs the informed consent form; no previous history of chronic pain; full-term, singleton pregnant women undergoing caesarean section under elective lumbar stiffness combined with anesthesia; ASA Classes I-II; BMI 18 - 30 kg/m2

Exclusion criteria

Exclusion criteria: Patients who are unwilling to cooperate with refusal to sign informed consent; Those with contraindications to lumbar hard combined anesthesia; Patients with a history of previous chronic pain, receiving or not receiving analgesic medications; severe pathological obstetric conditions (hypertensive syndrome of pregnancy, pre-eclampsia, eclampsia, placenta previa, placental abruption, etc.); Those who are known to be allergic to the drugs used during surgery or related contraindications (hypertension, glaucoma, etc.).

Design outcomes

Primary

MeasureTime frame
wound hyperalgesia index;

Secondary

MeasureTime frame
visual analogue scale;Ramssy Sedation Scale Score;Edinburgh Postnatal Depression Scale (EPDS);incidence of side reacton;

Countries

China

Contacts

Public ContactYushan Ma

West China Second Hospital of Sichuan University

mayushan_123@163.com18180609225

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026