pre diabetes mellitus
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) The age is 35-70 years old; (2) Overweight/obese patients (BMI = 24 kg/m2, where obesity is defined as BMI = 28 kg/m2) (3) The pre diagnosis of diabetes is based on the Guidelines for the Prevention and Treatment of diabetes in China (2020 Edition): including impaired fasting blood glucose (fasting blood glucose 6.1 - 6.9 mmol/L) and/or impaired glucose tolerance (glucose load 2h blood glucose 7.8 - 11.1 mmol/L); (4) Agree to participate in this study and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) Take diabetes or obesity drugs; (2) Infectious disease (active period) or being treated with drugs for acute disease; (3) Heart disease, chronic kidney disease, mental system disease, cancer; (4) Have received weight loss surgery; (5) Planned pregnancy, pregnancy or lactation women; (6) Patients without weight loss intention; (7) He has participated in other clinical studies within three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BMI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Glucose metabolism index;HOMA-IR;blood fat;Blood metabolites;Proportion of macronutrients in daily diet;Weight loss compliance; | — |
Countries
China
Contacts
The First Affiliated Hospital of Wenzhou Medical Univerity