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The predictive value of orexin on postoperative cognitive impairment in elderly patients with perioperative sleep disorder after spinal anesthesia

The predictive value of orexin on postoperative cognitive impairment in elderly patients with sleep disorder perioperative after spinal anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300069805
Enrollment
Unknown
Registered
2023-03-27
Start date
2023-03-27
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

perioperative sleep disorder postoperative cognitive impairment

Interventions

Group of elderly patients with perioperative sleep disorders:None

Sponsors

Department of Anesthesiology,Chifeng Municipal Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) Age greater than 65 years; (2) Can cooperate with experiments and related evaluation of patients; (3) Persons receiving intraspinal anesthesia; (4) ASA = Level II (5) Volunteer to participate in clinical trials and sign an informed consent form.

Exclusion criteria

Exclusion criteria: (1) Patients with craniocerebral injury; (2) Patients with severe drug dependence; (3) Patients with mental and psychological disorders; (4) Patients with cognitive impairment; (5) Unable to cooperate with relevant experiments and test patients (6) Missing cerebrospinal fluid and blood samples; (7) Preoperative anesthesia medication; (8) Patients undergoing intraoperative anesthesia changes (9) Participated in other clinical trials within 3 months prior to inclusion in the study.

Design outcomes

Primary

MeasureTime frame
perioperative sleep qualitu;postoperative cognitive impairment;orexin;—

Countries

China

Contacts

Public ContactZhou Qi

Chifeng Municipal Hospital

zhouqi1020818@sina.com13848877505

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026