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A multicenter prospective clinical study of anticoagulant treatment with common heparin in sepsis

A multicenter prospective clinical study of anticoagulant treatment with common heparin in sepsis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300069804
Enrollment
Unknown
Registered
2023-03-27
Start date
2023-04-01
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

heparin anticoagulant group:Heparin was used for anticoagulant therapy
Control group:Placebo (normal saline)

Sponsors

Department of Emergency, Rujin Hospital, Shanghai Jiao Tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged >=18 years and 10mg/L and D-Dimer > 5mg/L.4. Sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1) Pregnant or lactating women; 2) Allergic to ordinary heparin or VitC; 3) Have blood system diseases; 4) Anticoagulant or antiplatelet drug therapy; 5) Patients with diseases with potential bleeding risk such as severe brain trauma, brain aneurysm, arteriovenous malformation, bronchiectasis, digestive tract ulcer, or 24 hours after severe trauma or surgical operation

Design outcomes

Primary

MeasureTime frame
28d mortality rate;—

Secondary

MeasureTime frame
arterial blood gas analysis;liver function;renal function;myocardial enzyme;coagulation function;SOFA scoring;ISTH scoring;—

Countries

China

Contacts

Public ContactMa Li

Department of Emergency, Rujin Hospital, Shanghai Jiao Tong University School of Medicine

malipostgraduate2@163.com+86 15921615410

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026