Wilson's disease
Conditions
Interventions
treatment group:Gandou Fumu recipe + western medicine
control group:Gandou Fumu recipe Simulant + western medicine
Sponsors
The First Affiliated Hospital of Anhui University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age between 18 and 65 years old, gender unlimited; 2. Patients who meet the diagnostic criteria of disease; 3. Patients who meet the diagnostic criteria of liver fibrosis; 4. TCM syndrome differentiation belongs to liver and kidney deficiency, phlegm, and blood stasis syndrome; 5. Informed consent of patients or legal representatives, and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with fulminant liver failure (with or without hemolytic anemia) and decompensated cirrhosis; 2. Pregnant or lactating women, or women preparing for pregnancy; 3. Concomitant with other serious diseases (such as malignant tumors, hematopoiesis, and other diseases).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| liver stiffness measurement; | — |
Secondary
| Measure | Time frame |
|---|---|
| hyaluronic acid;type ? collagen;laminin;type ? procollagen peptide;Sheth index;Gaussian Process Regression (GPR) index;Fibrosis 4 (FIB-4) index;Aspartate aminotransferase-to-Platelet Ratio Index (APRI index);24-hour urine copper;uniform Wilson’s disease rating scale;traditional chinese medicine (TCM) syndrome scale;Color Doppler ultrasound of digestive system;Safety index; | — |
Countries
China
Contacts
Public ContactWang Meixia
The First Affiliated Hospital of Anhui University of Chinese medicine
Outcome results
None listed