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The alterations of subclasses, proteomics and functions of high-density lipoprotein in obesity

The alterations of subclasses, proteomics and functions of high-density lipoprotein in obesity

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300069768
Enrollment
Unknown
Registered
2023-03-24
Start date
2023-04-01
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Interventions

Normal weight group:N/A

Sponsors

Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. age 18-65 years old, males or females. 2. Informed and signed consent to participate in this study. 3. subjects with obesity with BMI=28kg/m2, or subjects without obesity with BMI between 18.5 kg/m2 and 24 kg/m2.

Exclusion criteria

Exclusion criteria: 1.Pregnant or lactating women 2.Smoking or excessive alcohol consumption 3.Suffering from cardiovascular disease such as coronary heart disease, heart failure, stroke, etc. 4.End-stage liver or kidney disease 5.Suffering from other diseases, such as diabetes, hyperthyroidism, hypothyroidism, severe infection, tumor, autoimmune disease, etc. 6.Major surgery or traumatic events in the past 2 months; 7.Taken drugs for regulating lipid metabolism, resisting oxidative stress or non-steroidal anti-inflammatory drugs in the past 3 months.

Design outcomes

Primary

MeasureTime frame
HDL proteomics;Cholesterol efflux capacity of HDL;

Secondary

MeasureTime frame
Anti-oxidative capacity of HDL;Anti-inflammation index;

Countries

China

Contacts

Public ContactYuling Zhang

Sun Yat-sen Memorial Hospital, Sun Yat-sen University

zhyul@mail.sysu.edu.cn13711675897

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026