Nonalcoholic fatty liver disease
Conditions
Interventions
Intervention group:Fatty liver Data Analysis and Intervention Software was used to manage the intervention group
Control group:Health education and lifestyle guidance are provided by professional clinicians and dietitians/health managers via phone and wechat
Sponsors
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: ? The diagnosis of NAFLD is consistent with the diagnosis of NAFLD; ? the age range is from 18 to 65 years old. 24kg/m2=BMI=35kg/m2; (3) Patients had smart phones in line with the operating environment of the software program of this study, and had the ability to use the software program of this study through guidance; ? The patients agreed to participate in the study, receive review and follow-up on time, and sign the informed consent.
Exclusion criteria
Exclusion criteria: ? Genetic metabolic or autoimmune liver disease with hepatophil virus and non-hepatophil virus infection drug/poison/alcohol/biliary liver injury, cirrhosis or any end-stage liver disease; ? Liver or extrahepatic malignancies; ? Diabetic patients with unstable blood glucose control (patients treated with insulin, HbA1C > 9%); ? Pregnant and lactating women; (5) suffering from other major cardiovascular and cerebrovascular diseases, liver and kidney diseases; (6) Patients with severe respiratory, heart, brain and other diseases who cannot complete diet and exercise intervention and need other treatment; ? Concomitant mental illness, including anxiety or depression; ? Researchers believe that there are objects that are not suitable for inclusion factors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weight loss rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Liver fat attenuation paramete;Liver stiffness value (LSM);Body mass index (BMI);Waist to hip ratio;Liver function (AST, ALT);Fasting plasma glucose;Fasting insulin;glycosylated hemoglobin;Adverse/serious adverse event rates; | — |
Countries
china
Contacts
Public ContactSun Chao
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed