Vegetative state patient
Conditions
Interventions
Group 1 of vegetative state patients:propofol 0mg/kg/h
Group 2 of vegetative state patients:propofol 1.0mg/kg/h
Group of moyamoya disease patients:propofol 1.5mg/kg/h
Group of spinal cord electrical stimulation (SCS):None
Sponsors
Peking University International Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1)VS patients: aged 18-65 years; No central drugs used 24 hours before anesthesia; Patients diagnosed with VS by CRS-R score in neurosurgery (already tracheotomy); 2) Patients with moyamoya disease: aged 18-65 years; Intracranial bypass surgery was performed; Unconsciousness disorder, no contraindications
Exclusion criteria
Exclusion criteria: Patients with uncontrolled hypertension and diabetes, history of cardiac surgery, single/multiple organ failure, severe clotting disorders, epilepsy, pacemaker implantation, refusal to study, and contraindications to rsfMRI.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effect of different doses of sedative and hypnotic drugs on the relative power of electroencephalogram in postoperative awakening therapy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Effects of sedative and hypnotic drugs on cerebral functional network and EEG under rsfMRI in patients with VS and Moyamoya disease;Effect of general anesthesia on stress response of VS patients undergoing SCS implantation;VS Whether the patient needs sedative medication; | — |
Countries
China
Contacts
Public ContactLan Yao
Peking University International Hospital
Outcome results
None listed