Disorders of consciousness after craniocerebral injury
Conditions
Interventions
Experimental group:intermittent theta burst stimulation
Control group:intermittent theta burst sham stimulation
Sponsors
The First Affiliated Hospital of Gannan Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Age = 18 years old, gender is not limited. (2) Patients with first-episode stroke or craniocerebral trauma. (3) Patients in a vegetative or minimally conscious state 1 to 3 months after onset; (4) Patients or their immediate family members voluntarily participated in this study and signed the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with serious heart, liver or kidney diseases and unstable vital signs. (2) Patients who are taking antiepileptic, antidepressant and other sedative drugs. (3) Contraindications to transcranial magnetic therapy such as intracranial metal built in, excessive intracranial pressure, etc. (4) Those who are participating in other clinical studies. (5) Patients who have poor compliance and are prone to missing visits. (6) Patients who, in the opinion of the investigator, are not suitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Transcranial magnetism sitimulation combined with EEG (TMS-EEG);Functional brain imaging assessment (fNIRS);Transcranial magnetic motor evoked potentials (TMS-MEP);CRS-R Rating Scale; | — |
Countries
China
Contacts
Public ContactLuo Yun
The First Affiliated Hospital of Gannan Medical University
Outcome results
None listed