Non-small cell lung cancer
Conditions
Interventions
Postoperative low risk patients, standard care:No intervention
Postoperative middle/high risk patients, standard care:No intervention
Sponsors
The Sixth Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: a) Signed informed consent form; b) Willing to comply with the study protocol and follow-up procedures; c) Age =18 years; d) Histological or cytological confirmation of one of the five subtypes of lung adenocarcinoma and confirmed as a primary, untreated patient with IA-IIA stage (according to the 8th edition of AJCC staging criteria); e) Surgical patients with curative resection, negative margins, and margins >2cm or >tumor diameter, no lymph node metastasis, and no pleural retraction; f) Patients must have measurable lesions (according to RECIST 1.0 criteria); g) Performance status evaluated by ECOG score of 0-1.
Exclusion criteria
Exclusion criteria: a) Received any systemic anticancer treatment for NSCLC, including cytotoxic chemotherapy, targeted therapy, or experimental therapy; b) Received any local radiation therapy for NSCLC; c) Had any other cancer except for cervical carcinoma in situ, cured basal cell carcinoma, or non-muscle-invasive bladder cancer [including Ta and Tis] within five years before the start of this study; d) Had any unstable systemic disease (including active infection, uncontrolled hypertension, unstable angina, angina pectoris that started within the last 3 months, congestive heart failure [= New York Heart Association [NYHA] II], myocardial infarction [within 6 months before enrollment], severe arrhythmia requiring medication, liver, kidney or metabolic diseases); e) Ever or currently has interstitial lung disease; f) Known human immunodeficiency virus (HIV) infection; g) Any malabsorption condition; h) Pregnant or lactating women; i) Other situations that the researchers deemed inappropriate for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease Free Survival;Disease Recurrence; | — |
Countries
China
Contacts
Public ContactLiao Hongying
The Sixth Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed