COVID-19
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. The new coronavirus infection was confirmed within 24 hours, and the nucleic acid RNA of the nasopharyngeal swab was positive; 2. Age >= 12 years old, weight >= 40 Kg; 3. The childbearing object must agree to use high-efficiency contraceptive methods.
Exclusion criteria
Exclusion criteria: 1. Previous history of COVID-19 treatment; 2. Known history of active liver disease; 3. Patients receiving renal dialysis or known to have moderate to severe renal impairment; 4. Known human immunodeficiency virus (HIV) infection; 5. Suspected or confirmed concurrent active systemic infection other than COVID-19 infection; 6. Has a history of allergies or other contraindications to any component of the research intervention; 7. Currently or expected to use any drug or substance that is highly dependent on CYP3A4 enzyme clearance or strongly induces CYP3A4 enzyme; 8. Pregnant or lactating women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CT value of COVID-19; | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of hospitalization;Adverse drug reaction;The reactivation of COVID-19; | — |
Countries
China
Contacts
Wenzhou Central Hospital