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Determination of the median effective dose of dexmedetomidine for the inhibition of emergence agitation in pre-school children undergoing tonsillectomy: A retrospective dose-response study

Determination of the median effective dose of dexmedetomidine for the inhibition of emergence agitation in pre-school children undergoing tonsillectomy: A retrospective dose-response study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300069681
Enrollment
Unknown
Registered
2023-03-23
Start date
2023-04-01
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tonsillectomy and/or adenoidectomy

Interventions

group 0.2:Dexmedetomidine
group 0.25:Dexmedetomidine
group 0.3:Dexmedetomidine
group 0.35:Dexmedetomidine
group 0.4:Dexmedetomidine
group 0.45:Dexmedetomidine
group 0.5:Dexmedetomidine

Sponsors

Anqing Municipal Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: From January 2020 to December 2022, 140 children (ASA I-II) who underwent tonsillectomy and/or adenoidectomy and underwent PACU resuscitation were selected

Exclusion criteria

Exclusion criteria: All children with abnormal function of important organs (such as heart, liver, lung, kidney, etc.) should be excluded, and children with other preoperative comorbidities and psychiatric and neurological history should also be excluded.

Design outcomes

Secondary

MeasureTime frame
The incidence of agitation;Postoperative pain;Incidence of bradycardia;—

Primary

MeasureTime frame
median effective dose;—

Countries

China

Contacts

Public ContactBai-Yun Wei

Anqing municipal hospital Anhui province

w2bwang@sina.com13500558021

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026