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Comparative study of the effects of cyclopofol and propofol on hemodynamics, postoperative recovery and cognitive function in thoracoscopic surgery

Comparative study of the effects of cyclopofol and propofol on hemodynamics, postoperative recovery and cognitive function in thoracoscopic surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300069650
Enrollment
Unknown
Registered
2023-03-22
Start date
2023-03-25
Completion date
Unknown
Last updated
2023-10-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary space occupying

Interventions

Group C:Cyclopofol was used for induction and maintenance of anesthesia
Group P:Propofol was used for induction and maintenance of anesthesia

Sponsors

The First Affiliated Hospital of Guangxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective thoracoscopic surgery; 2. Patients whose ASA classification is I-II; 3. Patients aged between 18 and 60 years; Male or female; 4. Patients whose BMI is 18-30kg/m2; 5. Patients consent to the inclusion.

Exclusion criteria

Exclusion criteria: 1. Patients with severe cardiopulmonary, hepato-renal system obvious abnormalities; 2. Patients with cognitive dysfunction or psychiatric symptoms before surgery; 3. Patients with communication disorders; 4. Chronic drug, alcohol, and psychotropic substance abuse; 5. The experimental drug in this study is contraindicated; 6. Patients who did not agree to participate in this study.

Design outcomes

Primary

MeasureTime frame
Hemodynamic parameters;

Secondary

MeasureTime frame
Mini-mental state examination (MMSE);Delirium Scale Score;Recovery condition;Cumulative intraoperative use of sufentanil and remifentanil;ICU stay time;Postoperative hospital stay;

Countries

China

Contacts

Public ContactLifang Lan

The First Affiliated Hospital of Guangxi Medical University

975536930@qq.com+86 158 0781 2473

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026