Hip replacement
Conditions
Interventions
Experimental group:Esketamine controlled intravenous analgesia after surgery
Control group 1:Post-operative sufentanil controlled intravenous analgesia
Control group 2:Postoperative continuous iliofascial nerve block
Sponsors
Gansu Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1) Patients undergoing unilateral hip replacement; 2) patients aged 18-85 years; 3) ASA grade I~III; 4) Clear consciousness, basic reading comprehension ability, vision and hearing basic normal; 6) No history of mental illness or cognitive dysfunction, able to express their feelings in language; 7) Participate in this study voluntarily, and be able to understand and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1) Allergic or contraindicated to the drug used in the study; 2) Participate in other clinical studies within 3 months before being enrolled in this study; 3) Lower extremity motor and sensory nerve injury; 4) Patients with dysfunction of heart, lung and other important organs; 5) Patients with a history of mental illness or cognitive impairment and a recent history of taking psychiatric drugs; 6) Patients who cannot understand and communicate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain VAS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ramsay calm score;Bromage motor block score;Tactile and temperature scores of affected limb;Anxiety (SAS) and depression (SDS) scores before and 48h after surgery;Harris hip function scores 1 month and 3 months after surgery;First time out of bed activity;Length of stay;Patient and doctor satisfaction;Number of therapeutic analgesia and drug use of Tramadol; | — |
Countries
China
Contacts
Public ContactYan Wenjun
Gansu Provincial People's Hospital
Outcome results
None listed