Hyperthyroidism secondary to chronic kidney disease
Conditions
Interventions
Group A:Stripping surrounding water isolation before ablation
Group B:Traditional liquid isolation
Group C:Ablation with 5mm working electrode not completely surrounded by water
Group D:Ablation with 7mm working electrode not completely surrounded by water
Sponsors
fujian provincial hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: efer to the guidelines of the Global Kidney Disease Prognosis Improvement Organization (KDIGO) [9] and the consensus of experts in clinical practice of surgery for hyperparathyroidism secondary to chronic renal failure: 1) dialysis patients with SHPT in phase 5 of chronic kidney disease; 2) In patients with resistance to calcium-sensitive receptor agonists, vitamin D and its analogues, continuous full-segment parathyroid hormone (PTH>800pg/ml; 3) 99mTc-MIBI dual-phase imaging and neck ultrasound showed hyperplastic parathyroid glands in all patients; 4) No severe bleeding disorder, cardiac discomfort or uncontrolled hypertension.
Exclusion criteria
Exclusion criteria: 1) 99mTc-MIBI dual-phase imaging found ectopic parathyroid glands outside the neck; 2) Patients with primary hyperparathyroidism. 3) Laryngoscopy showed abnormal vocal cord movement; 4) Abnormal coagulation function test (prothrombin time>25 seconds, prothrombin activity<40%, platelet count<100*109/L) 5) The patient refused the RFA; 6) Severe cardiopulmonary dysfunction;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intraoperative blood loss;Operation time;hospital stay;ablation time per unit volume;occurrence of recurrent laryngeal nerve;Parathyroid hormone levels;Serum calcium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum C-reactive protein (CRP);tumor necrosis factor- a ( TNF- a);interleukin-6 (IL-6); | — |
Countries
China
Contacts
Public ContactSongsong Wu
Fujian provincial hospital
Outcome results
None listed