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A study on the changes of resting-state neural networks in patients undergoing cardiopulmonary bypass

A study on the changes of resting-state neural networks in patients undergoing cardiopulmonary bypass

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300069614
Enrollment
Unknown
Registered
2023-03-22
Start date
2021-05-01
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

perioperative neurocognitive disorder

Interventions

surgery group:None
healthy control group:none

Sponsors

the Second Affiliated Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-75 years old; 2. Right-handed; 3. Informed consent was obtained from each patient.

Exclusion criteria

Exclusion criteria: 1. Preoperative Mini-Mental State Examination (MMSE) score =27; 2. Individuals with drug, alcohol or tobacco addicts; 3. A history of head trauma or craniocerebral surgery; 4. Patients with central nervous system diseases and mental disorders; 5. Chronic medical illness known to induce encephalopathy; 6. Patients with severe visual or communication deficits; 7. Contraindication to magnetic resonance scanning.

Design outcomes

Primary

MeasureTime frame
brain functional connectivity;cognitive assessment score;—

Secondary

MeasureTime frame
inflammatory factors;—

Countries

China

Contacts

Public ContactYao Hao

the Second Affiliated Hospital of Nanjing Medical University

yaohao@njmu.edu.cn+86 15895852288

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 6, 2026