apnea of prematurity
Conditions
Interventions
experimental group:Prone position ventilation 30?
experimental group:Prone position ventilation 15?
experimental group:Prone position ventilation 0?
Supine ventilation 0?:Supine ventilation 0?
Sponsors
Qujing Women's and Children's Health Care Hospital area
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: ? Approved by the hospital ethics committee and informed consent of the child's family; ? Gestational age of preterm infants =34 weeks, body weight less than 2kg, 1h ~ 7d in neonatal period; ? Apnea occurs within 48 hours after birth; ? Recurrent apnea does not occur more than 3 times within 1 h; Diagnostic criteria for premature apnea According to Expert Consensus on the diagnosis and treatment of premature apnea (Chinese Journal of Pediatrics, 2022, 60 (7) : 627-632) : Respiratory interruption occurred in premature infants =20 s, or s accompanied by decreased heart rate or oxygen saturation.
Exclusion criteria
Exclusion criteria: : Parents who did not want to participate in the study and did not cooperate with follow-up visits; Neuromuscular diseases such as perinatal asphyxia, intracranial hemorrhage, intracranial infection, hydrocephalus, convulsion, congenital myopathy, or neurological diseases; Respiratory diseases such as hypoxemia, hypercapnia, airway obstruction, paralysis of diaphragm or vocal cord, pneumothorax, pulmonary hemorrhage, lung infection; Digestive diseases such as feeding intolerance, neonatal necrotizing enterocolitis, peritonitis; Cardiovascular diseases such as heart failure, hemodynamic abnormalities of patent ductus arteriosus, severe congenital heart disease, severe hypovolemia, hypotension, hypertension; Hematological diseases such as anemia, polycythemia, severe hyperbilirubinemia; Metabolic and electrolyte disorders such as hypoglycemia, hyperaminemia, hypothyroidism, hyposodium, hypersodium, hypermagnesium, hyperkalemia; Others include severe infection, temperature instability, maternal anesthetics and magnesium sulfate, vagal reflex (gastric tube insertion, excessive neck flexion and extension).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Apnea awakening time;The number of apnea episodes;Apnea onset time;Apnea onset time;Oxygen saturation at apnea onset;Oxygen saturation at apnea onset;There is no stimulation to recover from apnea attack;Heart rate during apnea seizure;Heart rate during apnea seizure;Minimum heart rate during apnea episodes;Minimum heart rate during apnea episodes;Whether positive pressure ventilation is required during apnea attacks;Whether positive pressure ventilation is required during apnea attacks;Whether a tracheal intubation is necessary during apnea episodes;Whether a tracheal intubation is necessary during apnea episodes; | — |
Countries
China
Contacts
Public ContactLiu junling
Qujing Women's and Children's Health Care Hospital area
Outcome results
None listed