chronic knee pain
Conditions
Interventions
Exposure group:Intra-articular combined targeted injection of PRP
Non-exposure group:Intra-articular injection of PRP
Sponsors
West China Hosipital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1 ) Knee pain for 3 months or more in the past year ; 2 ) Visual analogue scale ( VAS ) = 40 ; 3 ) Age over 18 years old and under 80 years old ; 4 ) Willing to comply with the treatment plan and sign informed consent.
Exclusion criteria
Exclusion criteria: 1 ) Combine one or more non-knee problems in lower limb that affect daily activities; 2 ) Intra-articular injection of steroids or PRP and other biological agents within 4 weeks; 3 ) Recieved other treatments that may have an impact on the observation indicators of PRP treatment in the past year, such as biological therapy including stem cells, and systemic immunosuppressive drugs; 4 ) Pregnant and lactating women; 5 ) With infectious diseases; 6 ) Fever > 38.0 °C of unknown origin within three days ; 7 ) History of alcohol and drug abuse; 8 ) Moderate to severe anxiety, depression and other mental illness ; 9 ) Do not understand Mandarin, do not understand Chinese characters ;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual analogue scale, VAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| WOMAC;Lysholm; | — |
Countries
China
Contacts
Public ContactQian Wang
West China Hospital, Sichuan University
Outcome results
None listed