Respiratory system complications in patients undergoing tonsillectomy and/or adenoidectomy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age: 3-65 years old;2.ASA grading ?~?;3. Estimated anesthesia operation time =120min;4. Informed consent signed by the patient or the legal client.
Exclusion criteria
Exclusion criteria: 1. Body mass index (BMI) =14 kg/m2 or = 32.9kg /m2;Weight =10kg;2. Patients with a history of opioid allergy;3. Analgesic sedatives, emetic agents and antipruritus agents were used 24 hours before surgery;4. Patients with body temperature higher than 38? or symptoms of acute upper respiratory tract infection within 24 hours before surgery;5. Patients with a history of bronchial asthma;6. Patients diagnosed with moderate to severe sleep apnea syndrome before surgery;7. Patients with difficult airway or previous history of recovery from abnormal anesthesia were evaluated before surgery;8. Renal function injury (BUN and or Cr> upper limit of normal);9. Liver function injury (ALT and or AST>1.5 times the upper limit of normal);10.6 Patients with a history of severe head trauma or intracranial hypertension within months;11. Patients with mental or neurological diseases, or patients unable to express their wishes correctly;12 Patients with a history of long-term sedative and analgesic drugs or monoamine oxidase inhibitors;13. Expected surgical blood loss greater than 100ml;14. Those who have participated in clinical trials of other drugs within the last month;15. Patients who cannot receive ASA or FLACC score for various reasons;16. Patients with other conditions were not considered suitable for inclusion.17. Abnormal breath-holding test;18. Have not quit smoking in recent half a month;19. Patients with high blood pressure or accompanied by irregular heart rate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemodynamic parameters within five minutes after induction of intubation;Sore throat immediately after surgery;Throat pain score one hour after surgery;Incidence of PONV; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time for extubation;Incidence of analgesic use;The grade for EIC; | — |
Countries
China
Contacts
Yichang Central People's Hospital of Hubei Province