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Median effective dose of intravenous lidocaine for airway complications in tonsillectomy patients

Median effective dose of intravenous lidocaine for airway complications in tonsillectomy patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300069567
Enrollment
Unknown
Registered
2023-03-21
Start date
2023-04-01
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory system complications in patients undergoing tonsillectomy and/or adenoidectomy

Interventions

Age =15 years old:Different doses of lidocaine are administered continuously through an intravenous pump
Age>15 years old:Different doses of lidocaine are administered continuously through an intravenous pump

Sponsors

Yichang Central People's Hospital of Hubei Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age: 3-65 years old;2.ASA grading ?~?;3. Estimated anesthesia operation time =120min;4. Informed consent signed by the patient or the legal client.

Exclusion criteria

Exclusion criteria: 1. Body mass index (BMI) =14 kg/m2 or = 32.9kg /m2;Weight =10kg;2. Patients with a history of opioid allergy;3. Analgesic sedatives, emetic agents and antipruritus agents were used 24 hours before surgery;4. Patients with body temperature higher than 38? or symptoms of acute upper respiratory tract infection within 24 hours before surgery;5. Patients with a history of bronchial asthma;6. Patients diagnosed with moderate to severe sleep apnea syndrome before surgery;7. Patients with difficult airway or previous history of recovery from abnormal anesthesia were evaluated before surgery;8. Renal function injury (BUN and or Cr> upper limit of normal);9. Liver function injury (ALT and or AST>1.5 times the upper limit of normal);10.6 Patients with a history of severe head trauma or intracranial hypertension within months;11. Patients with mental or neurological diseases, or patients unable to express their wishes correctly;12 Patients with a history of long-term sedative and analgesic drugs or monoamine oxidase inhibitors;13. Expected surgical blood loss greater than 100ml;14. Those who have participated in clinical trials of other drugs within the last month;15. Patients who cannot receive ASA or FLACC score for various reasons;16. Patients with other conditions were not considered suitable for inclusion.17. Abnormal breath-holding test;18. Have not quit smoking in recent half a month;19. Patients with high blood pressure or accompanied by irregular heart rate.

Design outcomes

Primary

MeasureTime frame
Hemodynamic parameters within five minutes after induction of intubation;Sore throat immediately after surgery;Throat pain score one hour after surgery;Incidence of PONV;

Secondary

MeasureTime frame
Time for extubation;Incidence of analgesic use;The grade for EIC;

Countries

China

Contacts

Public ContactGong Yuan

Yichang Central People's Hospital of Hubei Province

gy-yc@163.com+86 13986746821

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026