Patients undergoing hysteroscopy under general anesthesia with laryngeal mask airway
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: The first part of this study (the effect of intravenous lidocaine on the ED50 and ED95 of propofol for successful placement of a double-lumen laryngeal mask airway, and the incidence of perioperative complications in adult patients): patients with ASA physical status I or II, aged 18-60 years, fasted from solid foods up to 6 hours and clear liquids up to 2 hours before surgery were included. The second part of this study (the effect of intravenous lidocaine on the ED50 and ED95 of propofol for successful placement of a double-lumen laryngeal mask airway, and the incidence of perioperative complications in elderly patients):patients with ASA physical status I or II, aged 60-80 years, fasted from solid foods up to 6 hours and clear liquids up to 2 hours before surgery were included.
Exclusion criteria
Exclusion criteria: Exclusion criteria were as follows: patients with body max index(BMI )>28 kg/m2 or BMI<18 kg/m2;patients with body weight < 40 kg; patients with difficult airway, recent history of upper respiratory tract infection and gastroesophageal reflux; patients allergic to local anesthetics, propofol, fentanil or other drugs related to this study; patients with severe liver and kidney dysfunction, endocrine diseases, metabolic diseases, cardiovascular diseases, respiratory system diseases or central nervous system diseases; patients who received sedatives, analgesics, and drugs that may affect the metabolism of local anesthetics for a long time or within 7 days; patients who received other experimental drugs or participated in other clinical trials within 3 months before the study; patients addicted to alcohol or drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| LMA insertion is invalid or effective; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total amount of propofol induction;Extubation time;hypotension;atropine consumption; | — |
Countries
China
Contacts
West China Second University Hospital