mild hyperlipidemia combined with obesity
Conditions
Interventions
Sponsors
Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age 18~65 years old, no ethnic limit, no gender limit; 2. Patients diagnosed with mild hyperlipidemia and overweight/obesity: (1) Hypertriglyceridemia (1.7mmol/L=TG<2.3mmol/L); (2) hypercholesterolemia (5.2mmol/L=TC<6.2mmol/L, or 3.4mmol/L=LDL-C<4.1mmol/L); (3) Mixed hyperlipidemia (1.7mmol/L=TG<2.3mmol/L and 5.2mmol/L=TC<6.2mmol/L, or 1.7mmol/L=TG<2.3mmol/L and 3.4mmol/L=LDL-C<4.1mmol/L, or 1.7mmol/L = TG < 2.3mmol/L and 5.2mmol/L = TC <6.2mmol/L and 3.4mmol/ L/ L=LDL-C<4.1mmol/L) (4) Diagnostic criteria for overweight/obesity: BMI= 24 kg/m2; 3. Have communication and cognitive skills, and be able to adhere to long-term medication.
Exclusion criteria
Exclusion criteria: (1) Those who are receiving lipid-lowering drugs; (2) Hyperlipidemia caused by secondary causes, such as nephrotic syndrome, liver disease, hypothyroidism, renal failure, etc.; (3) Severe diabetes, hypertriglyceridemia, cerebrovascular disease and other major diseases that require immediate treatment; (4) Suffering from heart disease, immune system disease, acute onset of chronic diseases, infectious diseases, malignant tumors, etc.; (5) Patients with serious primary diseases and psychosis such as liver, kidney and hematopoietic system; (6) pregnant or lactating women; (7) Those who are allergic and allergic to test drugs; (8) Patients with a history of gallbladder surgery and digestive tract polyp surgery; (9) Those who use antibiotics or take probiotics and other prebiotic preparations within 3 months of recruitment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood lipids;body composition;waistline;gut microbiota;serum lipid metabolites;bile acid; | — |
Secondary
| Measure | Time frame |
|---|---|
| hepatic and renal function;fasting blood-glucose;fasting insulin;serum inflammatory factors; | — |
Countries
China
Contacts
Public ContactWuyuanhua
The First Affiliated Hospital of Guizhou University of Chinese Medicine
Outcome results
None listed