post-COVID-19 fatigue syndrome
Conditions
Interventions
Observation group:Renshen Guben oral liquid
Control group:Placebo
Sponsors
Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria for post-COVID-19 fatigue syndrome; (2) Meet the diagnostic criteria of TCM Qi and Yin deficiency syndrome; (3) Age 18-70, gender unlimited; (4) The patient agreed to join the clinical study, voluntarily signed the informed consent, and agreed to participate in the visit, examination and treatment according to the requirements of the research protocol.
Exclusion criteria
Exclusion criteria: (1) combined with mental illness, such as severe anxiety and severe depression; (2) Secondary fatigue caused by drugs or other reasons; (3) patients with serious primary diseases of cardiovascular and cerebrovascular systems, liver, kidney and hematopoietic systems, malignant tumors, and other serious complications; (4) Pregnant or lactating women; (5) have received relevant treatment and may affect the observed effect indicators; (6) Patients suspected of having a history of drug abuse or other ineligible patients. (7) Allergic constitution and allergic to the drug. (8) Patients with uncontrolled hypertension (DBP > 100mmHg or SBP > 160 mmHg)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chalder scale score; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM syndrome score;EQ-5D-5L Quality of Life questionnaire score;CRP;TNF-a;IL-6;IL-8;CD3+ cell;CD4+ cell;CD8+ cell;NK cell;blood routine examination;hepatic and renal function; | — |
Countries
China
Contacts
Public ContactGuang Ji
Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed