birth defects
Conditions
Interventions
Group of special pregnant women:None
Sponsors
Obstetrics&Gynecology Hospital of Fudan University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Subjects in the training set and test set GDM pregnant group must meet all of the following criteria: 1. Complete patient sociological and clinical profile; 2. No pre-pregnancy diabetes, i.e., pre-pregnancy does not meet fasting blood glucose concentration >= 7.0 mmol/L or HbA1c level >= 6.5%; suffer from GDM after pregnancy, i.e. meets the diagnostic criteria for GDM. ogtt meets FTG >= 5.1 mmol/L, 1 h post-sugar administration blood glucose concentration >= 10.0 mmol/L, 2 h post-sugar administration blood glucose concentration >= 8.5 mmol/L, meets the above Any one of the above can confirm the diagnosis of GDM11; 3. Complete liver and kidney function examination data, no major medical or surgical diseases combined. Subjects in the training and test sets of normal pregnant control subjects must meet all of the following criteria: 1. Complete sociological and clinical profile of the subject; 2. No pre-pregnancy diabetes, i.e., no pre-pregnancy fasting blood glucose concentration >= 7.0 mmol/L or HbA1c level >= 6.5%; no post-pregnancy gestational diabetes, i.e., no one of the following three GDM diagnostic criteria: OGTT: FTG >= 5.1 mmol/L, 1 h post-sugar administration blood glucose concentration >= 10.0 mmol/L, 2 h post-sugar administration blood glucose concentration >= 8.5 mmol/L; 3. Complete information on liver and kidney function tests, no major medical or surgical diseases.
Exclusion criteria
Exclusion criteria: 1. Subjects with > 20% missing observations; 2. Other conditions deemed by the investigator as unsuitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy of early screening models for GDM; | — |
Secondary
| Measure | Time frame |
|---|---|
| Type of variables for the input model;Number of variables in the input model;Correlation of variables with the occurrence of GDM; | — |
Countries
China
Contacts
Public ContactXu Chenming
Obstetrics&Gynecology Hospital of Fudan University
Outcome results
None listed