Skip to content

Analysis of the characteristics of post-stroke cognitive impairment (PSCI) and the application of NfL level variation in early clinical intervention and comprehensive management

Analysis of the characteristics of post-stroke cognitive impairment (PSCI) and the application of NfL level variation in early clinical intervention and comprehensive management

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300069479
Enrollment
Unknown
Registered
2023-03-17
Start date
2023-03-17
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-stroke cognitive impairment

Interventions

Group of post-stroke cognitive impairment:no

Sponsors

The First People's Hospital of Kunshan
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. According to the clinical symptoms, signs and head MRI examination, the patient was diagnosed as acute cerebral infarction (onset time <= 14 days). According to "the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018" formulated by the Chinese Society of Neurology, at least one cognitive region was impaired in acute cerebral infarction. 2. First onset; 3. Aged 18-80 years; 4. No prodromal symptoms were observed before onset, and the cognitive function, motor function and social adaptation ability were all at normal levels; 5. Cooperate with physical examination and neuropsychological evaluation; 6. Signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Various reasons (including language disorders, visual disorders, consciousness disorders, etc.) can not complete the cognitive function evaluation; 2. History of cognitive impairment; Patients with mental disorders such as anxiety, depression and mental disorders had a Hamilton Depression Scale (HAMD) score >= 17; 3. Refusal to sign the informed consent form; 4. Failure to cooperate with follow-up studies; 5. mRS score was greater than 1 before the onset of stroke; 6. Chronic drug abuse or history of drug dependence.

Design outcomes

Primary

MeasureTime frame
cognition;

Countries

China

Contacts

Public ContactYan Zhang

The First People's Hospital of Kunshan

2573560757@qq.com+86 13962638897

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026