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Efficacy analysis of dexamethasone injection at different sites on mandibular impacted third molars extraction

Efficacy analysis of dexamethasone injection at different sites on mandibular impacted third molars extraction

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300069472
Enrollment
Unknown
Registered
2023-03-17
Start date
2021-04-01
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

impacted tooth

Interventions

Group 1:The patients in group 1 received a submucosal injection of 4 mg (0.8 ml) dexamethasone on the buccal side of the adjacent second molar before third molar surgery
Group 2:the patients in group 2 received it on the buccal side of extraction sockets before third molar surgery
Control group:The patients in the control group received a submucosal injection of 0.8 ml of normal saline on the buccal side of the adjacent second molar

Sponsors

Ningbo First Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 25 Years

Inclusion criteria

Inclusion criteria: 1. Aged 12-25 years; 2. Good overall health; 3. Both male and female, women need to avoid the physiological period; 4. The diagnosis was of mandibular impacted third molars, which met the Pell and Gregory classification of fully impacted teeth, and the root was not fully developed; 5. ASA rating I-II; 6. No hormone drugs were taken from 15 days before the start of the study to the end of the study; 7. Follow up can be coordinated one week after surgery.

Exclusion criteria

Exclusion criteria: 1. Patients with hypertension, diabetes, heart disease, thyroid function disease, hematopoietic system disease and other obvious tooth extraction contraindications; 2. Female patients during pregnancy, lactation, or menstruation; 3. Patients with cysts or other odontogenic lesions of the mandibular third molar; 4. Patients with a history of allergies or adverse reactions to the drugs used in this study; 5. Patients who are participating in other clinical trials; 6. Patients who withdraw midway; 7. Patients who cannot be followed up; 8. Swelling of the face and neck due to other reasons.

Design outcomes

Primary

MeasureTime frame
Lateral canthus of the eye to the gonion angle;Tragus to the commissure of the mouth;Tragus to the soft tissue pogonion;the maximum mouth opening;Visual Analogue Scale;Postoperative Symptom Severity(posse) scale;

Countries

China

Contacts

Public ContactYang Yong

Ningbo First Hospital

NBDYYY_yy@163.com18657465655

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026