Acute myocardial infarction
Conditions
Interventions
Healthy control group:none
Sponsors
The First Affiliated Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
20 Years to 75 Years
Inclusion criteria
Inclusion criteria: AMI patients: 1. Aged 20-75 years, regardless of gender; 2. Chest pain symptoms of myocardial ischemia; 3. Significant new ST-segment T-wave changes in the ECG and definitive diagnosis of non-ST elevation MI or ST elevation MI; 4. The reference value of cardiac troponin is at least above the upper 99th percentile; 5. Clear occlusion during acute PCI and angiography; 6. The first coronary artery reperfusion was successfully performed during PCI; Healthy controls(non-AMI): 1. Aged 20-75 years, regardless of gender; 2. Normal range electrocardiogram; 3. No known heart disease; 4. Computed tomography angiography results were classified as negative for coronary artery disease.
Exclusion criteria
Exclusion criteria: 1. Percutaneous coronary intervention for associated myocardial infarction; 2. Myocardial infarction associated with coronary artery bypass grafting; 3. Recurrent myocardial infarction or reinfarction; 4. Necrotizing myocardial injury caused by transcatheter aortic valve implantation or mitral valve clamp or arrhythmia ablation; 5. Myocardial damage or infarction associated with heart failure; 6. Atrial fibrillation and structural heart disease; 7. Other comorbidities that are not well controlled clinically (cancer, rheumatoid arthritis, liver or kidney disease, hematological disorders, chronic inflammation); 8. Patients with cognitive dysfunction and dementia; 9. Patients who do not want to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IL-17A;S100A8/9;Major adverse cardiovascular events;IGFBP5; | — |
Countries
china
Contacts
Public ContactXinli Li
The First Affiliated Hospital of Nanjing Medical University
Outcome results
None listed