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The role and mechanism of thrombospondin-2 in the regulation of hypertension and its complications and insulin resistance

The role and mechanism of thrombospondin-2 in the regulation of hypertension and its complications and insulin resistance

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300069422
Enrollment
Unknown
Registered
2023-03-15
Start date
2023-02-01
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertensive

Interventions

Hypertension and normal control group:None
PCOS and normal controls:None

Sponsors

The Third Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 79 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria 1. Patients diagnosed with essential hypertension for the first time according to the Guidelines for the Prevention and Treatment of Hypertension in Chinese Adults (2018 Edition); 2. Have not taken hypertension drugs, have not taken drugs affecting blood pressure in the last 3 months (such as oral contraceptives, etc.); 3. Aged 18-79 years; 4. Patients can understand the content of informed consent, mental health, communication barrier-free.

Exclusion criteria

Exclusion criteria: 1. Patients with diabetes mellitus were excluded; 2. Patients with severe acute and chronic diseases such as cardiovascular system, respiratory system, urinary system, nervous system, bone and motor system, blood and immune system, endocrine system, eye, ear, nose and throat; 3. Patients with infectious diseases or infectious diseases who are not suitable for enrollment; 4. Pregnant women or those preparing for pregnancy.

Design outcomes

Primary

MeasureTime frame
Thrombospondin 2;

Secondary

MeasureTime frame
FBG (fasting blood-glucose);blood lipid;liver renal function;Body Composition Analysis;blood pressure;blood routine examination;Female hormone 6;Urinary sodium;thyroid function;fasting insulin;urine albumin-creatinine ratio;OGTT, oral glucose tolerance test;

Countries

China

Contacts

Public ContactJian Yang/Xiaoxin Zhou

The Third Affiliated Hospital of Chongqing Medical University;The Third Affiliated Hospital of Chongqing Medical University

yangjianac@163.com+86 13708383337/13883761937

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026