Probiotics for postpartum health
Conditions
Interventions
Probiotic intervention group:Each person was given a dry vacuum packed probiotic bag
control group:None
Sponsors
Tsinghua University
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. The mother has no metabolic diseases such as diabetes; 2. The mother has no infectious diseases such as hepatitis B and HIV; 3. The mother has no breast and breast diseases such as sunken nipple; 4. Postpartum weight is 5 kg or more higher than the pre-pregnancy weight.
Exclusion criteria
Exclusion criteria: 1. The mother has a severe mental condition that prevents her from cooperating well with researchers; 2. Oral probiotics or prebiotics within the last 4 weeks; 3. Have taken antibiotics or received any antibiotics or purgatory drugs in the last 4 weeks; 4. Severe diarrhea (watery stool more than 3 times a day for 3 consecutive days or more) in the last 4 weeks; 5. Severe constipation in the last 4 weeks (two or less bowel movements per week with difficulty defecating); 6. History of intestinal disease, other severe digestive diseases, such as colorectal polyps, colorectal cancer have been diagnosed; 7. People with depression at baseline screening.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnosis of postpartum depressive state;Body weight retention;Detection of body fat composition; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood gamma-aminobutyric acid, serotonin content detection;Detection of intestinal flora and specific colonization of intervention bacteria;Fecal SCFAs detection; | — |
Countries
China
Contacts
Public ContactAi Zhao
Tsinghua University
Outcome results
None listed