Depression
Conditions
Interventions
Control group:Pseudo-Transcranial Direct Current Stimulation
Healthy control group:No intervention
Sponsors
Ningbo Kangning Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Healthy control group: the method of public recruitment was adopted. The inclusion criteria included : 1. Normal mental examination; 2. Hamilton Depression Scale 17 (HAMD-17) score = 17 points; 4. Education level above primary school; 5. Those who sign the informed consent.
Exclusion criteria
Exclusion criteria: Exclusion criteria of healthy control group: 1. Serious physical disease; 2. Low intelligence or mental retardation (IQ < 90); 3. Pregnant women; 4. Previous history of mental disorders or family history of mental disorders; 5. History of psychoactive substance abuse. Depression group exclusion criteria: 1. Combined with physical diseases and organic brain diseases; 2. Comorbidities with other mental disorders; 3. Patients with severe suicidal tendencies; 4. Pregnant and lactating women; 5. Patients who have used any antipsychotic drugs or mood stabilizers in the last 2 weeks; Patients who have received electroconvulsive therapy within the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TMS-MEP (Transcranial Magnetic Stimulation Motor Evoked Potentials);TMS-EEG (Transcranial Magnetic Stimulation Electroencephalogram);HAMD (Hamilton Depression Rating Scale) score; | — |
Secondary
| Measure | Time frame |
|---|---|
| HAMA (Hamilton Rating Scale Anxiety) score; | — |
Countries
China
Contacts
Public ContactYubo Wang
Ningbo Kangning Hospital
Outcome results
None listed