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Effect of transcutaneous auricular vagus nerve stimulation combined with auricular point pressing on upper limb function in recovery period after stroke

Effect of transcutaneous auricular vagus nerve stimulation combined with auricular point pressing on upper limb function in recovery period after stroke

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300069403
Enrollment
Unknown
Registered
2023-03-15
Start date
2023-03-15
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Observation group 1:transcutaneous auricular vagus nerve stimulation
Observation group 2:auricular point pressing
Observation group 3:transcutaneous auricular vagus nerve stimulation combined with auricular point pressing

Sponsors

The Second Affiliated Hospital of Dalian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. First onset, unilateral limb hemiplegia, duration of 2 weeks to 3 months, aged 25-80 years; 2. No obvious cognitive impairment, MMSE score (illiteracy > 17 points, elementary school > 20 points, junior high school and above > 24 points); 3. Brunnstrom upper limb motor function assessment >= stage 2; 4. All subjects were aware of the research protocol and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Mental disorders and epilepsy in the past; 2. Other neurological and musculoskeletal diseases that may interfere with the evaluation of this study; 3. Combined with serious diseases such as cardiovascular and cerebrovascular systems, digestive system; 4. Those who are not suitable for ear stimulation, such as auricle infection, People with ulcers or scars; 5. People who are not suitable for brain stimulation, such as metal implants in the brain, hyperalgesia, injury or inflammation in the brain; 6. The heart rate is lower than 60, and instruments and equipment such as pacemakers and cochlear implants are placed in the body; 7. Previously received vagus nerve surgery or had metal in the skull.

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer assessment-upper extremity, FMA-UE;activity of daily living, ADL;cortical latency, CL;

Countries

China

Contacts

Public ContactWang Litong

The Second Affiliated Hospital of Dalian Medical University

litongwanglv@163.com+86 17709876587

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026