Patients with severe mechanical ventilation
Conditions
Interventions
Group 1:Routine rehabilitation treatment measures
Group 2:Routine rehabilitation therapy plus 20% maximum inspiratory pressure for inspiratory muscle training
Group 3:Routine treatment plus 40% maximum inspiratory pressure for inspiratory muscle training
Group 4:Routine rehabilitation therapy plus 50% maximum inspiratory pressure for inspiratory muscle training
Sponsors
General Hospital of the Southern Theater of the Chinese People's Liberation Army
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. ICU or HDU patients; 2. Over 18, under 90; 3. Awakened and able to cooperate; 4. Can provide informed consent and actively participate in training; 5. Glasgow >= 12 points; 6. FiO2 < 0.5; 7. MEWS < 3 points; 8. Ability to trigger spontaneous respiration during ventilation.
Exclusion criteria
Exclusion criteria: 1. The patient is unconscious or unable to cooperate; 2. Hemodynamic instability (i.e., systolic blood pressure>180 or130 times/min); 3. Severe arrhythmia; 4. Myocardial infarction and respiratory instability (oxygen saturation<88%); 5. Spinal cord injury above C5 seriously affects respiratory function; 6. Spinal scoliosis, flail chest, spinal internal fixation and other diseases that seriously damage the chest wall and rib movement; 7. Patients with severe sedation and respiratory muscle paralysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maximum inspiratory pressure;diaphragm thickness; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bathel index;Borg score;Fatigue resistance index;Diaphragm mobility;Blood gas analysis; | — |
Countries
China
Contacts
Public ContactHuang Huai
General Hospital of the Southern Theater of the Chinese People's Liberation Army
Outcome results
None listed