Mild depression disorder
Conditions
Interventions
Experimental group:Acupuncture
Control group:Sham acupuncture
Sponsors
Guangdong Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of depressive episode in ICD-10, DSM-V, and the diagnostic criteria of "depression disease" in ZY/T001.1-94; 2. Age 18 ~ 65 years old, junior high school education or above; 3. The PHQ-9 scale score in the initial screening was > 5 points; 17 Hamilton Depression Scale (HAMD-17) scores >= 8 points and < 17 points were evaluated by interviews with psychopharmacologists. 4. Right-handed; 5. Sign the informed consent and volunteer to participate in this study.
Exclusion criteria
Exclusion criteria: 1. People with suicidal tendencies; 2. Previous diagnoses of mental disorders, schizophrenia, bipolar disorder, substance abuse (such as alcohol dependence) or other mental disorders; 3. Epileptic seizure history or strong positive family history of epilepsy, organic brain disease and serious physical disease; 4. Patients taking antidepressants within 6 weeks (including 6 weeks); 5. Pregnancy, preparation for pregnancy or lactation; 6. Patients with skin lesions or skin diseases, severe diabetes, tumors and major organ insufficiency or serious internal diseases of liver, kidney, cardiovascular, endocrine, respiratory and hematopoietic systems; 7. Patients with other central or peripheral neuropathy; 8. Subjects who cannot obtain stable cerebral blood flow velocity envelope by transcranial Doppler ultrasound or who have not explored and monitored blood vessels.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient Health Questionnaire-9, PHQ-9;Hamilton Depression Scale-17, HAMD-17; | — |
Secondary
| Measure | Time frame |
|---|---|
| Beck Depression Inventory-13, BDI-13;Pittsburgh sleep quality index, PSQI;Attention to Positive and Negative Information Scale, APNI;Self-rating depression scale, SDS;Hamilton Anxiety Scale;the vividness of viual imagery questionnaire, VVIQ;Cognitive function measurement paradigm;EEG;transcranial Doppler, TCD;functional magnetic resonance imaging, fMRI; | — |
Countries
China
Contacts
Public ContactWenbin Fu
Guangdon Provincial Hospital of Chinese Medicine
Outcome results
None listed