Myopia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion Criteria of High Myopia: Spherical equivalent = 26.0mm. Inclusion Criteria of Control Subjects: 1. Spherical equivalent > -0.50 D; 2. Age and gender-matched with myopia group; 3. No family or personal history of glaucoma or other ocular diseases.
Exclusion criteria
Exclusion criteria: 1. Secondary myopia; 2. LASIK surgery history; 3. History of autoimmunity disease; 4. Severe health problems precluding follow-up; 5. Ocular media opacity; 6. Plan to move from the area within the next 10 years.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference of choroidal and retinal vasculature (CVI, FAZ area, FAZ circularity, VD, VDI and FD) for myopia progression between high myopia and normal children;Difference of choroidal and retinal vasculature (CVI, FAZ area, FAZ circularity, VD, VDI and FD) between adults with and without high myopia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Difference of choroidal and retinal vasculature (CVI, FAZ area, FAZ circularity, VD, VDI and FD) between high myopia and normal children at baseline;Difference of choroidal and retinal vasculature (CVI, FAZ area, FAZ circularity, VD, VDI and FD) between adults with and without high myopia at baseline;Difference of choroidal and retinal vasculature (CVI, FAZ area, FAZ circularity, VD, VDI and FD) in adults with different severity of high myopia; | — |
Countries
China
Contacts
Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong