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Clinical comparative study of dry eye before and after oral administration of a1a adrenergic receptor inhibitors

Clinical comparative study of dry eye before and after oral administration of a1a adrenergic receptor inhibitors

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300069351
Enrollment
Unknown
Registered
2023-03-14
Start date
2023-03-01
Completion date
Unknown
Last updated
2023-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry eye

Interventions

Medication group:Detection of dry eye

Sponsors

Qingdao Eye Hospital of Shandong First Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: Dry eye with prostate hyperplasia in male patients; Aged 50-80 years. Dry eye with lower urinary tract syndrome in female patients; Aged 50-80 years;

Exclusion criteria

Exclusion criteria: Long-term contact lens wearing; intense pulsed laser or thermal pulsation treatment within 3 months; corneal refractive surgery; Concomitant ocular surface diseases (e.g. pterygium, conjunctival mass, etc.); Combined with immune-related eye diseases, such as Sjogren's syndrome, Stephens-Johnson syndrome, etc., or systemic immune diseases, rheumatoid arthritis, ankylosing spondylitis, systemic lupus erythematosus, pemphigoid.

Design outcomes

Primary

MeasureTime frame
Shirmer test I;Ocular surface disease index;Corneal epithelial staining score;

Secondary

MeasureTime frame
Tear function;Shirmer test II;Lipiview ocular surface interferometer;

Countries

China

Contacts

Public ContactYangyang Zhang

Qingdao Eye Hospital of Shandong First Medical University

fff993541@163.com+86 188 6625 5751

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026