Knee Osteoarthritis
Conditions
Sponsors
Shanghai Municipal Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of KOA set by American College of Rheumatology; 2. Male or female patients aged 40 years or older; 3. Mild to moderate radiographic medial tibiofemoral osteoarthritis (Kellgren - Lawrence score from 1 to 3) in at least one knee; 4. WOMAC pain score >= 40 (visual analog version, range from 0 to 100, higher indicating more pain) on at least one of five questions; 5. Volunteer to participate in the trial and provide written informed consent form.
Exclusion criteria
Exclusion criteria: 1. History of knee surgery or combined with tumor, tuberculosis, osteomyelitis in knee joints; 2. Arthroscopy in the past 6 months or intra-articular injection of steroid or hyaluronic acid in the past 3 months; 3. Major medical or physical conditions determined by doctors to preclude exercise, including serious acute or chronic organic diseases of cardiovascular, hepatic, renal, cerebrovascular and hematopoietic systems, recent stroke, psychiatric disease, active cancer; 4. Have participated in strength training more than 30 minutes per week in the past 3 months; 5. Have participated in other clinic trials in the past 4 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Western Ontario and McMaster Universities Osteoarthritis Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Isokinetic dynamometry;Gait and Surface electromyography test;Short Form for Quality of Life, SF-36;Dosage of NSAIDs; | — |
Countries
China
Contacts
Public ContactYao Fei
Shanghai Municipal Hospital of Traditional Chinese Medicine
Outcome results
None listed