Final kidney disease
Conditions
Interventions
Sponsors
Changzhou Second People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients with end-stage renal disease; 2. Age 18-65 years old; 3. Have been on regular dialysis for not less than 3 months, 3 times a week, 4 hours each time; 4. The patient's vital signs are basically stable and in good condition, and the expected survival period is more than 2 years; 5. Dialysis using arteriovenous fistula; 6. cTNI >= 0.034 µg/L; 7. In line with the principles of medical ethics, patients and their families voluntarily signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Autar deep vein thrombosis risk assessment scale score >= 7 points; 2. Patients with severe hypertension (poor blood pressure control, systolic blood pressure > 160mmHg); 3. Patients with severe swelling of lower extremity muscles or joints, limb movement disorders, and inability to tolerate ischemic preconditioning intervention; 4. Patients with severe infection or acute cardiovascular and cerebrovascular diseases within the past 6 months; 5. Uncontrolled infection and unexplained fever and vasculitis, Raynaud's disease, diabetic foot, capillary fragility, multiple peripheral neuropathy; 6. Coagulation dysfunction or active visceral hemorrhage and malignant tumor; 7. Consciousness disorder, mentally ill patients; 8. Patients who plan to go out in the near future and cannot continue to receive dialysis in the hemodialysis room.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TroponinI, TNI;two-dimensional speckle tracking for echocardiography; | — |
Secondary
| Measure | Time frame |
|---|---|
| creatine kinase isoenzymes, CK-MB;C-reactive protein, CRP;Blood pressure; | — |
Countries
China
Contacts
Public ContactLiu Tongqiang
Changzhou Second People's Hospital
Outcome results
None listed