healthy person
Conditions
Interventions
Experimental group:cTBS + iTBS, after a one-week washout period, Sham cTBS+iTBS
Control group:Sham cTBS + iTBS, after a one-week washout period, cTBS + iTBS
Sponsors
Wuxi Mental Health Center/Wuxi Cental Rehabilitation Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years; 2. No central nervous system and mental disorders; 3. No history of drug or alcohol dependence; 4. No contraindications for TMS and fNIRS; 5. Participate voluntarily and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Any neurological diseases; 2. History of epilepsy; 3. No serious mental or physical illness; 4. Had TMS adverse reactions; 5. Take drugs that affect cortical excitability; 6. Pregnancy; 7. History of lower extremity surgery; 8. Failure to induce a response to TMS in the anterior tibial muscle; 9. Poor compliance or inability to cooperate with the test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Motor evoked potential amplitude; | — |
Secondary
| Measure | Time frame |
|---|---|
| Resting motion threshold;functional near-infrared imaging; | — |
Countries
China
Contacts
Public ContactBin Su
Wuxi Mental Health Center/Wuxi Cental Rehabilitation Hospital
Outcome results
None listed