depression
Conditions
Interventions
Case series:NA
Sponsors
Wuxi Mental Health Center
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. The sample is derived from the remaining sample of clinical testing, and the remaining sample size meets: >= 1 mL of human serum sample; 2. Meet the storage requirements, that is, the samples must be stored at room temperature after collection and centrifuged within 12 hours after collection. It is then stored protected from light at -60 °C until analysis; 3. Patients are aged 18-60 years old, gender is not limited; 4. Patients 3 days ± sample collection meet one of the following clinical conditions: (1) First episode, not receiving any medication, Hamilton (HAMD) scale assessment: 24 Hamilton Depression Scale overall score > 20; (2) Meet the diagnostic criteria for depression in the Primary Diagnosis and Treatment Guidelines for Depression (2021), Hamilton (HAMD) scale assessment: 24 Hamilton Depression Scale overall scores > 20 points; (3) Patients diagnosed with depression according to the Primary Care Guidelines for Depression (2021) improved after medical treatment and were rated on the Hamilton (HAMD) scale: The total score of the 24 Hamilton Depression Scales was < 8.
Exclusion criteria
Exclusion criteria: 1. The sample showed coagulation or hemolysis; 2. Incorrect collection or storage of samples; 3. The subject has other psychiatric diseases at the same time; 4. Those who are dependent on drugs or alcohol or have a history of abuse; 5. Patients with neurological lesions, brain trauma, cardiovascular and cerebrovascular diseases, severe liver and kidney dysfunction, diabetes and other major physical diseases; 6. Pregnant or lactating women; 7. Those who have surgery or other major medical history within 6 months; 8. Are receiving hormonal therapy; 9. Subjects who the investigator believes have other factors that are not suitable to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Metabolomics; | — |
Countries
China
Contacts
Public ContactWang Jun
Wuxi Mental Health Center
Outcome results
None listed