Upper Airway Cough Syndrome (UACS)
Conditions
Interventions
Trial Group:Dextromethorphan + Sanfeng Tongqiao Diwan
Placebo Group:Dextromethorphan + Sanfeng Tongqiao Diwan Simulator (Does not contain Active Ingredient of Sanfeng Tongqiao Diwan)
Sponsors
The First Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-70 years old; 2. Meet the diagnostic criteria of chronic cough UACS; Nasal symptoms are preferred; 3. The informed consent process complies with the regulations, and the informed consent form is signed.
Exclusion criteria
Exclusion criteria: 1. Chronic bronchitis, cough variant asthma, gastroesophageal reflux cough, eosinophilic bronchitis, bronchiectasis, allergic asthma, allergic cough and congenital respiratory diseases; 2. Patients with serious heart, liver, kidney, brain, mental and neurological diseases and any tumor; 3. Pregnancy, lactation or planned pregnancy; 4. Those who regularly used nasal inhaled glucocorticoids, antihistamines, leukotriene receptor antagonists, etc. within one week, which interfere with the study effect, are recommended to be included if they have passed five drug half-lives before enrollment; 5. Those who are known to be allergic to the study drug or drug composition; 6. Those who are participating in other clinical trials; 7. Smoking patients are recommended to be excluded; 8. According to the judgment of the researcher, it is not suitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptom relief score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Chinese version of Leicester cough Inventory (LCQ-MC);visual analogue scale, VAS; | — |
Countries
ChIna
Contacts
Public ContactJing Li
The First Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed