chronic atrophic gastritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for chronic atrophic gastritis; 2. Present with one or both of the discomfort symptoms of abdominal pain or bloating in the past week, and one or both symptoms are at least moderately severe (overall symptom score >=4); 3. Aged 18-75 years, no gender limit; 4. Understand and agree to participate in this study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Autoimmune gastritis (chronic atrophic gastritis type A); 2. Positive C-13 urea breath test at enrollment (Hp infected); 3. Patients diagnosed with gastroesophageal reflux disease (GERD) by endoscopy or other examination; 4. Patients with diagnosed or unable to rule out malignant tumors, especially esophageal and gastric cancers; Patients with peptic ulcer or other upper digestive tract lesions such as Barrett's esophagus; 5. Patients with serious lesions in vital organs of the whole body (heart, liver, kidney, lung, etc.); 6. Pregnant and lactating patients; 7. Patients with infectious diseases such as tuberculosis, hepatitis and AIDS; 8. A history of alcohol, drug or illicit drug use; 9. Patients who have used other stomach-stimulating agents, mucosal protective agents or acid suppressors in the past 2 weeks; 10. Have received acupuncture therapy or are participating in other clinical research projects.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Abdominal pain and bloating symptom relief rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall symptom score;Pepsinogen?, ?;Gastrin-17;Operative link on gastritis assessment;Operative link on gastric intestinal metaplasia assessment;Self-rating Anxiety Scale;Self-rating Depression Scale;12-item Short-form Health Survey;Safety assessment; | — |
Countries
China
Contacts
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine