aortic dissection
Conditions
Interventions
Regular dose group:Coenzyme Q10 Treatment (50mg/250ml/day)
High dose group:Coenzyme Q10 Treatment (400mg/250ml/day)
Control group:Placebo Treatment (250ml/day)
Sponsors
Beijing Anzhen Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >=18 years; 2. The imaging diagnosis was type A aortic dissection; 3. The first appearance of symptoms related to aortic dissection was less than 14 days from the time of visit; 4. The aorta surgical team judged that they did not have surgical indications or the patient and his family refused surgical treatment; 5. Understand the risks of clinical trials and sign informed consent; 6. Promise to abide by the research procedures and cooperate with the implementation of the whole process of research.
Exclusion criteria
Exclusion criteria: 1. Trauma-associated aortic dissection; 2. Dissection leads to severe aortic valve insufficiency or massive pericardial effusion; 3. The pseudolumen has been completely thrombosed; 4. Pregnant patients during pregnancy; 5. Complicated with infection that is difficult to control; 6. With malignant tumor, the expected life span is less than one year; 7. Complicated with severe coronary heart disease, heart failure and other basic diseases; 8. Also participate in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All-cause mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| False lumen thrombosis;Aortic regurgitation;Pericardial tamponade;Splanchnic hypoperfusion; | — |
Countries
China
Contacts
Public ContactJiang Wenjian
Beijing Anzhen Hospital
Outcome results
None listed