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Effects of intermittent lung distension on respiratory function during and after surgery in elderly patients undergoing laparoscopic radical bowel cancer resection in Trendelenburg's position

Effects of intermittent lung distension on respiratory function during and after surgery in elderly patients undergoing laparoscopic radical bowel cancer resection in Trendelenburg's position

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300069270
Enrollment
Unknown
Registered
2023-03-10
Start date
2022-12-05
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bowel cancer

Interventions

Experimental group:Volume-controlled ventilation+Intermittent bulging
Control group:Volume-controlled ventilation

Sponsors

The First Affiliated Hospital of Gannan Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. American Society of Anesthesiologists (ASA) Grade I-III; 2. Selective laparoscopic radical resection of bowel cancer; 3. Aged 65-80 years; 4. Body Mass Index (BMI) 18-28 kg/m^2; 5. Agree to sign informed consent for clinical study.

Exclusion criteria

Exclusion criteria: 1. Patients with multiple chronic diseases who cannot tolerate surgery and anesthesia; 2. A long history of smoking; 3. Patients with severe heart, liver and kidney insufficiency; 4. Arterial oxygen saturation (SpO2) <=95% when entering the operating room at rest; 5. Patients with COPD, bronchial asthma, emphysema, pulmonary bullae, bronchiectasis and spontaneous pneumothorax in the past.

Design outcomes

Primary

MeasureTime frame
Lung ultrasound score;Pulmonary dynamic compliance;Oxygenation index;

Secondary

MeasureTime frame
Heart rate;Mean arterial pressure (MAP);SpO2;PetCO2;Peak airway pressure;

Countries

China

Contacts

Public ContactGuo Rui

The First Affiliated Hospital of Gannan Medical University

haiou2018guo@163.com+86 159 0707 4021

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026