Qi-zhi-xin-xiong phenomes of Xiong-bi-xin-tong
Conditions
Interventions
Control group:Coronary heart disease routine western medicine standard treatment drug therapy(CHD)
Experimental group:Standard western medicine treatment for CHD as mentioned above combined with Chai-hu-shu-gan-san
Sponsors
The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria for disease group: (1) In line with the traditional Chinese medicine industry standard of the People's Republic of China ''TCM Internal medicine Syndrome Diagnosis and Curative Effect Criteria'' (ZY/T001.1-94) TCM chest obstruction heartache qi stagnation cardiothoracic syndrome dialectical diagnosis basis, syndrome classification; Those who meet the diagnostic criteria of coronary heart disease and the diagnostic criteria of cardiac function grade I-II; (2) Those who meet the criteria for syndrome differentiation of chest obstruction, heartache, qi stagnation and cardiothoracic syndrome by 3 deputy director of traditional Chinese and Western medicine or above physicians; (3) Patients who meet the diagnostic criteria of coronary heart disease and the diagnostic criteria of cardiac function grade I-II; (4) Aged between 40 and 75 years (including 40 and 75); (5) Volunteer to participate in the experimental research and have signed the informed consent; (6) No intestinal infection within one month; Do not use antibiotics and probiotic preparations within one month, do not drink yogurt; (7) Have not taken similar proprietary Chinese medicine or traditional Chinese medicine decoction within one month; (8) The patient is informed and agrees to cooperate. 2. Inclusion criteria for the health group: (1) No gender limit, aged 40-75 years; (2) The syndrome differentiation of TCM constitution is peaceful quality; (3) No coronary heart disease, hypertension, kidney disease, tumor and other internal diseases; (4) The subject is informed and agrees to cooperate.
Exclusion criteria
Exclusion criteria: 1. Known allergy to test drug components; 2. Unable to cooperate, such as chest pain caused by other reasons; Coronary angiography or coronary CT results indicated that the main vessel (RCA, LM, LAD, LCX) was more than 75% stenosis; Severe heart valvular disease, pulmonary embolism, uncontrolled high blood pressure, and serious infections; Patients with severe diseases of liver and kidney, hematopoietic system and endocrine system; 3. Have a history of alcohol and drug abuse; 4. Patients who are participating in or have participated in other clinical trials within 12 weeks prior to the trial; 5. Pregnant or lactating patients or patients with fertility requirements; 6. Other patients should not participate according to the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Traditional Chinese Medicine Evidence Scale;Coronary heart disease laboratory indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Coronary heart disease imaging;Seattle Angina Questionnaire, SAQ;Self-rating Depression Scale, SDS;Self-rating Anxiety Scale, SAS;Adverse event; | — |
Countries
China
Contacts
Public ContactDuan Dayue
The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University
Outcome results
None listed